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Free Extracellular Diffusion Creates the Dpp Morphogen Gradient of the Drosophila Wing Disc

BACKGROUND: How morphogen gradients form has long been a subject of controversy. The strongest support for the view that morphogens do not simply spread by free diffusion has come from a variety of studies of the Decapentaplegic (Dpp) gradient of the Drosophila larval wing disc. RESULTS: In the pres...

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Autors principals: Zhou, Shaohua, Lo, Wing-Cheong, Suhalim, Jeffrey, Digman, Michelle A, Gratton, Enrico, Nie, Qing, Lander, Arthur D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338872/
https://ncbi.nlm.nih.gov/pubmed/22445299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.02.065
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