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Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms

The patterning of many developing tissues is organized by morphogens. Genetic and environmental perturbations of gene expression, protein synthesis and ligand binding are among the sources of unreliability that limit the accuracy and precision of morphogen-mediated patterning. While it has been foun...

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Bibliografische gegevens
Gepubliceerd in:J R Soc Interface
Hoofdauteurs: Lo, Wing-Cheong, Zhou, Shaohua, Wan, Frederic Y.-M., Lander, Arthur D., Nie, Qing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277094/
https://ncbi.nlm.nih.gov/pubmed/25551154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.1041
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