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Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms

The patterning of many developing tissues is organized by morphogens. Genetic and environmental perturbations of gene expression, protein synthesis and ligand binding are among the sources of unreliability that limit the accuracy and precision of morphogen-mediated patterning. While it has been foun...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Lo, Wing-Cheong, Zhou, Shaohua, Wan, Frederic Y.-M., Lander, Arthur D., Nie, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277094/
https://ncbi.nlm.nih.gov/pubmed/25551154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.1041
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