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β-catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is an incurable disease, characterized by skeletal muscle weakness and wasting. Genetically, FSHD is characterized by contraction or hypomethylation of repeat D4Z4 units on chromosome 4, which causes aberrant expression of the transcription factor DUX4 f...
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| Publicado no: | J R Soc Interface |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277075/ https://ncbi.nlm.nih.gov/pubmed/25551153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0797 |
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