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Tumor Progression Locus 2-dependent Oxidative Burst Drives Phosphorylation of Extracellular Signal-regulated Kinase during TLR3 and 9 Signaling

Signal transduction via NFκB and MAP kinase cascades is a universal response initiated upon pathogen recognition by Toll-like receptors (TLRs). How activation of these divergent signaling pathways is integrated to dictate distinct immune responses to diverse pathogens is still incompletely understoo...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Kuriakose, Teneema, Rada, Balázs, Watford, Wendy T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276873/
https://ncbi.nlm.nih.gov/pubmed/25378393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587121
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