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Tumor Progression Locus 2 (Tpl2) Kinase Promotes Chemokine Receptor Expression and Macrophage Migration during Acute Inflammation

In autoimmune diseases, the accumulation of activated leukocytes correlates with inflammation and disease progression, and, therefore, the disruption of leukocyte trafficking is an active area of research. The serine/threonine protein kinase Tpl2 (MAP3K8) regulates leukocyte inflammatory responses a...

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Autors principals: Rowley, Sean M., Kuriakose, Teneema, Dockery, Lee M., Tran-Ngyuen, Thi, Gingerich, Aaron D., Wei, Lai, Watford, Wendy T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140933/
https://ncbi.nlm.nih.gov/pubmed/24713702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559344
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