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Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8(+) T Cell Responses and Protects against Influenza Virus

Mitogen-activated protein kinase (MAP) cascades are important in antiviral immunity through their regulation of interferon (IFN) production as well as virus replication. Although the serine-threonine MAP kinase tumor progression locus 2 (Tpl2/MAP3K8) has been implicated as a key regulator of Type I...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kuriakose, Teneema, Tripp, Ralph A., Watford, Wendy T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524623/
https://ncbi.nlm.nih.gov/pubmed/26241898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005038
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