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Development and Characterization of Pepducins as G(s)-biased Allosteric Agonists
The β(2)-adrenergic receptor (β(2)AR) is a prototypical G protein-coupled receptor that mediates many hormonal responses, including cardiovascular and pulmonary function. β-Agonists used to combat hypercontractility in airway smooth muscle stimulate β(2)AR-dependent cAMP production that ultimately p...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276837/ https://ncbi.nlm.nih.gov/pubmed/25395624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618819 |
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