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Rescue of germline transmission from chimeras by IVF after sperm analysis
Successful production of genetically modified mouse lines is dependent on germline transmission (GLT) of mutant alleles from chimeras. When natural mating fails to achieve GLT due to male infertility, sickness, or other problems, sperm can be harvested from chimeras and used for assisted reproductiv...
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| Publicado no: | Transgenic Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276497/ https://ncbi.nlm.nih.gov/pubmed/25080098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-014-9819-7 |
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