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Combining sperm plug genotyping and coat color chimerism predicts germline transmission
There has been a significant increase in the use of C57BL/6N-derived ES cells for the production of gene knockout mice. However, the potential for germline transmission (GLT) from chimeras on this genetic background has been observed to be highly variable. Using coat color as an indicator of somatic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838463/ https://ncbi.nlm.nih.gov/pubmed/23860911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-013-9731-6 |
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