Convenient Synthesis of (18)F-Radiolabeled R-(−)-N-n-propyl-2-(3-fluoropropanoxy-11-hydroxynoraporphine

Aporphines are attractive candidates for imaging D(2) receptor function because, as agonists rather than antagonists, they are selective for the receptor in the high affinity state. In contrast, D(2) antagonists do not distinguish between the high and low affinity states, and in vitro data suggests...

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Publicado en:J Labelled Comp Radiopharm
Autores principales: Sromek, Anna W., Zhang, Shaohui, Akurathi, Vamsidar, Packard, Alan B., Li, Wei, Alagille, David, Morley, Thomas J., Baldwin, Ronald, Tamagnan, Gilles, Neumeyer, John L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275395/
https://ncbi.nlm.nih.gov/pubmed/25400260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3246
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