Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes

BACKGROUND: To date, few PET tracers for in vivo labeling of red blood cells (RBCs) are available. In this study, we report the radiosynthesis and in vitro and in vivo evaluation of (11)C and (18)F sulfonamide derivatives targeting carbonic anhydrase II (CA II), a metallo-enzyme expressed in RBCs, a...

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書誌詳細
主要な著者: Gheysens, Olivier, Akurathi, Vamsidhar, Chekol, Rufael, Dresselaers, Tom, Celen, Sofie, Koole, Michel, Dauwe, Dieter, Cleynhens, Bernard J, Claus, Piet, Janssens, Stefan, Verbruggen, Alfons M, Nuyts, Johan, Himmelreich, Uwe, Bormans, Guy M
フォーマット: Artigo
言語:Inglês
出版事項: Springer 2013
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561128/
https://ncbi.nlm.nih.gov/pubmed/23316861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-3-4
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