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Solid-Phase Synthesis and Fluorine-18 Radiolabeling of CycloRGDyK

Solid-phase peptide synthesis, head-to-tail cyclization, and subsequent radiolabeling provided a reproducible, simple, rapid synthetic method to generate the cyclic peptide radiotracer cRGDyK([(18)F]FBA). Herein is reported the first on-resin cyclization and (18)F-radiolabeling of a cyclic peptide (...

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Detalles Bibliográficos
Publicado en:Org Biomol Chem
Autores principales: Davis, Ryan A., Lau, Kevin, Hausner, Sven H., Sutcliffe, Julie L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111556/
https://ncbi.nlm.nih.gov/pubmed/27714190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob01636g
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