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Evaluation of the Cardiotoxicity of Mitragynine and Its Analogues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

INTRODUCTION: Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant with opioid-like effects for the treatment o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Jun, Wei, Heming, Wu, Jianjun, Jamil, Mohd Fadzly Amar, Tan, Mei Lan, Adenan, Mohd Ilham, Wong, Philip, Shim, Winston
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275233/
https://ncbi.nlm.nih.gov/pubmed/25535742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115648
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