Evaluation of the cardiotoxicity of mitragynine and its analogues using human induced pluripotent stem cell-derived cardiomyocytes.

INTRODUCTION:Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant with opioid-like effects for the treatment of...

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Main Authors: Jun Lu, Heming Wei, Jianjun Wu, Mohd Fadzly Amar Jamil, Mei Lan Tan, Mohd Ilham Adenan, Philip Wong, Winston Shim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4275233?pdf=render
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