Evaluation of the Cardiotoxicity of Mitragynine and Its Analogues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

INTRODUCTION: Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant with opioid-like effects for the treatment o...

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Vydáno v:PLoS One
Hlavní autoři: Lu, Jun, Wei, Heming, Wu, Jianjun, Jamil, Mohd Fadzly Amar, Tan, Mei Lan, Adenan, Mohd Ilham, Wong, Philip, Shim, Winston
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275233/
https://ncbi.nlm.nih.gov/pubmed/25535742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115648
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