Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples

We analyzed the in situ molecular correlates of infection from cancer patients treated with reovirus. Melanoma, colorectal, and ovarian cancer samples from such patients showed variable infection of the cancer cells but not the intermingled benign cells. RT in situ PCR showed most cancer cells conta...

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Vydáno v:Mod Pathol
Hlavní autoři: Nuovo, Gerard J, Garofalo, Michela, Valeri, Nicola, Roulstone, Vicki, Volinia, Stefano, Cohn, David E, Phelps, Mitch, Harrington, Kevin J, Vile, Richard, Melcher, Alan, Galanis, Evanthia, Sehl, Sarah, Adair, Rob, Scott, Karen, Rose, Ailsa, Toogood, Giles, Coffey, Matthew C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275064/
https://ncbi.nlm.nih.gov/pubmed/22699519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2012.95
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