The CCR5Δ32 Polymorphism in Brazilian Patients with Sickle Cell Disease

Background. Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because i...

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Vydáno v:Dis Markers
Hlavní autoři: Lopes, Mariana Pezzute, Santos, Magnun Nueldo Nunes, Faber, Eliel Wagner, Bezerra, Marcos André Cavalcanti, Hatzlhofer, Betânia Lucena Domingues, Albuquerque, Dulcinéia Martins, Zaccariotto, Tânia Regina, Ribeiro, Daniela Maria, Araújo, Aderson da Silva, Costa, Fernando Ferreira, Sonati, Maria de Fátima
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274860/
https://ncbi.nlm.nih.gov/pubmed/25548430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/678246
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