Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.

Monocyte-derived foam cells figure prominently in rupture-prone regions of atherosclerotic plaques. Peripheral blood monocytes in culture can produce certain enzymes that degrade extracellular matrix, known as matrix metalloproteinases (MMPs). Lipid-laden macrophages may thus contribute to weakening...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Galis, Z S, Sukhova, G K, Kranzhöfer, R, Clark, S, Libby, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831299/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.402
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!