Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence

BACKGROUND: Epigenetic alterations of specific genes have been reported to be related to colorectal cancer (CRC) transformation and would also appear to be involved in the early stages of colorectal carcinogenesis. Little data are available on the role of these alterations in determining a different...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Rengucci, Claudia, De Maio, Giulia, Gardini, Andrea Casadei, Zucca, Mattia, Scarpi, Emanuela, Zingaretti, Chiara, Foschi, Giovanni, Tumedei, Maria Maddalena, Molinari, Chiara, Saragoni, Luca, Puccetti, Maurizio, Amadori, Dino, Zoli, Wainer, Calistri, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274757/
https://ncbi.nlm.nih.gov/pubmed/25091577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0065-x
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