Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence

BACKGROUND: Epigenetic alterations of specific genes have been reported to be related to colorectal cancer (CRC) transformation and would also appear to be involved in the early stages of colorectal carcinogenesis. Little data are available on the role of these alterations in determining a different...

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Bibliografski detalji
Izdano u:J Exp Clin Cancer Res
Glavni autori: Rengucci, Claudia, De Maio, Giulia, Gardini, Andrea Casadei, Zucca, Mattia, Scarpi, Emanuela, Zingaretti, Chiara, Foschi, Giovanni, Tumedei, Maria Maddalena, Molinari, Chiara, Saragoni, Luca, Puccetti, Maurizio, Amadori, Dino, Zoli, Wainer, Calistri, Daniele
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274757/
https://ncbi.nlm.nih.gov/pubmed/25091577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0065-x
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