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Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence

BACKGROUND: Epigenetic alterations of specific genes have been reported to be related to colorectal cancer (CRC) transformation and would also appear to be involved in the early stages of colorectal carcinogenesis. Little data are available on the role of these alterations in determining a different...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Rengucci, Claudia, De Maio, Giulia, Gardini, Andrea Casadei, Zucca, Mattia, Scarpi, Emanuela, Zingaretti, Chiara, Foschi, Giovanni, Tumedei, Maria Maddalena, Molinari, Chiara, Saragoni, Luca, Puccetti, Maurizio, Amadori, Dino, Zoli, Wainer, Calistri, Daniele
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274757/
https://ncbi.nlm.nih.gov/pubmed/25091577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0065-x
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