Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence

BACKGROUND: Epigenetic alterations of specific genes have been reported to be related to colorectal cancer (CRC) transformation and would also appear to be involved in the early stages of colorectal carcinogenesis. Little data are available on the role of these alterations in determining a different...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Rengucci, Claudia, De Maio, Giulia, Gardini, Andrea Casadei, Zucca, Mattia, Scarpi, Emanuela, Zingaretti, Chiara, Foschi, Giovanni, Tumedei, Maria Maddalena, Molinari, Chiara, Saragoni, Luca, Puccetti, Maurizio, Amadori, Dino, Zoli, Wainer, Calistri, Daniele
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274757/
https://ncbi.nlm.nih.gov/pubmed/25091577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0065-x
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