A Limited Antigen-Specific Cellular Response Is Sufficient for the Early Control of Mycobacterium tuberculosis in the Lung but Is Insufficient for Long-Term Survival

Mice that were transgenic for a T-cell receptor (TCR) specific for ovalbumin peptide(323-339) (DO11.10) were able to survive an infection with Mycobacterium tuberculosis for approximately 80 days. This limited early control of infection was associated with gamma interferon production, inducible nitr...

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Detalhes bibliográficos
Main Authors: Turner, Joanne, Dobos, Karen M., Keen, Marc A, Frank, Anthony A., Ehlers, Stefan, Orme, Ian M., Belisle, John T., Cooper, Andrea M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427451/
https://ncbi.nlm.nih.gov/pubmed/15213116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.3759-3768.2004
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