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Immunization with Native or Recombinant Streptococcus pneumoniae Neuraminidase Affords Protection in the Chinchilla Otitis Media Model

Streptococcus pneumoniae neuraminidase has been implicated as a virulence factor in the pathogenesis of pneumococcal otitis media. In this study, native neuraminidase was partially purified from cultures of S. pneumoniae by serial chromatography with DEAE-Sepharose and Sephacryl S-200. Recombinant n...

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書誌詳細
主要な著者: Long, J. P., Tong, H. H., DeMaria, T. F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC427438/
https://ncbi.nlm.nih.gov/pubmed/15213181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4309-4313.2004
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