Immunization with Native or Recombinant Streptococcus pneumoniae Neuraminidase Affords Protection in the Chinchilla Otitis Media Model

Streptococcus pneumoniae neuraminidase has been implicated as a virulence factor in the pathogenesis of pneumococcal otitis media. In this study, native neuraminidase was partially purified from cultures of S. pneumoniae by serial chromatography with DEAE-Sepharose and Sephacryl S-200. Recombinant n...

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Pubblicato in:	Infect Immun
Autori principali:	Long, J. P., Tong, H. H., DeMaria, T. F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15213181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.7.4309-4313.2004
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