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Immunization with Native or Recombinant Streptococcus pneumoniae Neuraminidase Affords Protection in the Chinchilla Otitis Media Model

Streptococcus pneumoniae neuraminidase has been implicated as a virulence factor in the pathogenesis of pneumococcal otitis media. In this study, native neuraminidase was partially purified from cultures of S. pneumoniae by serial chromatography with DEAE-Sepharose and Sephacryl S-200. Recombinant n...

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Autors principals: Long, J. P., Tong, H. H., DeMaria, T. F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC427438/
https://ncbi.nlm.nih.gov/pubmed/15213181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4309-4313.2004
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