Identification of Murine H2-D(d)- and H2-A(b)-Restricted T-Cell Epitopes on a Novel Protective Antigen, MPT51, of Mycobacterium tuberculosis

Both CD4(+) type 1 helper T (Th1) cells and CD8(+) cytotoxic T lymphocytes (CTL) play pivotal roles in protection against Mycobacterium tuberculosis infection. Here, we identified Th1 and CTL epitopes on a novel protective antigen, MPT51, in BALB/c and C57BL/6 mice. Mice were immunized with plasmid...

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Библиографические подробности

Опубликовано в::	Infect Immun
Главные авторы:	Suzuki, Mina, Aoshi, Taiki, Nagata, Toshi, Koide, Yukio
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2004
Предметы:	Microbial Immunity and Vaccines
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15213124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.7.3829-3837.2004
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