Identification of Murine H2-D(d)- and H2-A(b)-Restricted T-Cell Epitopes on a Novel Protective Antigen, MPT51, of Mycobacterium tuberculosis

Both CD4(+) type 1 helper T (Th1) cells and CD8(+) cytotoxic T lymphocytes (CTL) play pivotal roles in protection against Mycobacterium tuberculosis infection. Here, we identified Th1 and CTL epitopes on a novel protective antigen, MPT51, in BALB/c and C57BL/6 mice. Mice were immunized with plasmid...

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Hlavní autoři: Suzuki, Mina, Aoshi, Taiki, Nagata, Toshi, Koide, Yukio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC427431/
https://ncbi.nlm.nih.gov/pubmed/15213124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.3829-3837.2004
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