A PIK3C3–Ankyrin-B–Dynactin pathway promotes axonal growth and multiorganelle transport

Axon growth requires long-range transport of organelles, but how these cargoes recruit their motors and how their traffic is regulated are not fully resolved. In this paper, we identify a new pathway based on the class III PI3-kinase (PIK3C3), ankyrin-B (AnkB), and dynactin, which promotes fast axon...

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Pubblicato in:J Cell Biol
Autori principali: Lorenzo, Damaris Nadia, Badea, Alexandra, Davis, Jonathan, Hostettler, Janell, He, Jiang, Zhong, Guisheng, Zhuang, Xiaowei, Bennett, Vann
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274267/
https://ncbi.nlm.nih.gov/pubmed/25533844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201407063
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