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Bone Marrow Transplantation Improves Autoinflammation and Inflammatory Bone Loss in SH3BP2 Knock-In Cherubism Mice

Cherubism (OMIM#118400) is a genetic disorder in children characterized by excessive jawbone destruction with proliferation of fibro-osseous lesions containing a large number of osteoclasts. Mutations in the SH3-domain binding protein 2 (SH3BP2) are responsible for cherubism. Analysis of the knock-i...

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Bibliografiske detaljer
Udgivet i:Bone
Main Authors: Yoshitaka, Teruhito, Kittaka, Mizuho, Ishida, Shu, Mizuno, Noriyoshi, Mukai, Tomoyuki, Ueki, Yasuyoshi
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274253/
https://ncbi.nlm.nih.gov/pubmed/25445458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.10.021
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