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Nuclear receptor full-length architectures: confronting myth and illusion with high-resolution

The crystal structures of three nuclear receptor (NR) complexes have emerged to reveal their multi-domain architectures on DNA. These pictures provide unprecedented views of interfacial couplings between the DNA binding domains (DBDs) and ligand binding domains (LBDs). The detailed pictures contrast...

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Bibliografiske detaljer
Udgivet i:Trends Biochem Sci
Main Authors: Rastinejad, Fraydoon, Ollendorff, Vincent, Polikarpov, Igor
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274238/
https://ncbi.nlm.nih.gov/pubmed/25435400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.10.011
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