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Understanding Nuclear Receptor Form and Function Using Structural Biology

Nuclear receptors (NR) are a major transcription factor family whose members selectively bind small molecule lipophilic ligands and transduce those signals into specific changes in gene programs. For over two decades, structural biology efforts were directed exclusively on the individual ligand bind...

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Autori principali: Rastinejad, Fraydoon, Huang, Pengxiang, Chandra, Vikas, Khorasanizadeh, Sepideh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871882/
https://ncbi.nlm.nih.gov/pubmed/24103914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-13-0173
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