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High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of Osteoarthritis

Murine models of osteoarthritis (OA) and post-traumatic OA have been widely used to study the development and progression of these diseases using genetically engineered mouse strains along with surgical or biochemical interventions. However, due to the small size and thickness of murine cartilage, t...

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Bibliografske podrobnosti
izdano v:J Biomech
Main Authors: Nia, Hadi Tavakoli, Gauci, Stephanie, Azadi, Mojtaba, Hung, Han-Hwa, Frank, Eliot, Fosang, Amanda, Ortiz, Christine, Grodzinsky, Alan J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274208/
https://ncbi.nlm.nih.gov/pubmed/25435386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2014.11.012
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