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High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of Osteoarthritis

Murine models of osteoarthritis (OA) and post-traumatic OA have been widely used to study the development and progression of these diseases using genetically engineered mouse strains along with surgical or biochemical interventions. However, due to the small size and thickness of murine cartilage, t...

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Dettagli Bibliografici
Pubblicato in:J Biomech
Autori principali: Nia, Hadi Tavakoli, Gauci, Stephanie, Azadi, Mojtaba, Hung, Han-Hwa, Frank, Eliot, Fosang, Amanda, Ortiz, Christine, Grodzinsky, Alan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274208/
https://ncbi.nlm.nih.gov/pubmed/25435386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2014.11.012
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