High-Bandwidth AFM-Based Rheology Reveals that Cartilage is Most Sensitive to High Loading Rates at Early Stages of Impairment

Utilizing a newly developed atomic-force-microscopy-based wide-frequency rheology system, we measured the dynamic nanomechanical behavior of normal and glycosaminoglycan (GAG)-depleted cartilage, the latter representing matrix degradation that occurs at the earliest stages of osteoarthritis. We obse...

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Detalhes bibliográficos
Main Authors: Nia, Hadi Tavakoli, Bozchalooi, Iman S., Li, Yang, Han, Lin, Hung, Han-Hwa, Frank, Eliot, Youcef-Toumi, Kamal, Ortiz, Christine, Grodzinsky, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Molecular Machines, Motors, and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617437/
https://ncbi.nlm.nih.gov/pubmed/23561529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.02.048
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