Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor

[Image: see text] The EphA4 receptor is highly expressed in the nervous system, and recent findings suggest that its signaling activity hinders neural repair and exacerbates certain neurodegenerative processes. EphA4 has also been implicated in cancer progression. Thus, EphA4 inhibitors represent po...

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Julkaisussa:ACS Chem Biol
Päätekijät: Lamberto, Ilaria, Lechtenberg, Bernhard C., Olson, Erika J., Mace, Peter D., Dawson, Philip E., Riedl, Stefan J., Pasquale, Elena B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273976/
https://ncbi.nlm.nih.gov/pubmed/25268696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500677x
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