Docosahexaenoic Acid and Eicosapentaenoic Acid Antagonize the Proinflammatory Interactions of Pneumolysin with Human Neutrophils

Pneumolysin (4.18 ng/ml)-mediated influx of Ca(2+) and augmentation of the chemoattractant-activated generation of reactive oxidants was antagonized by pretreatment of human neutrophils with the omega-3 polyunsaturated fatty acids docosahexaenoic acid and eicosapentaenoic acid (1.25 to 5 μg/ml). The...

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izdano v:	Infect Immun
Principais autores:	Cockeran, Riana, Theron, Annette J., Feldman, Charles, Mitchell, Timothy J., Anderson, Ronald
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2004
Teme:	Host Response and Inflammation
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427396/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15213185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.7.4327-4329.2004
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