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Docosahexaenoic Acid and Eicosapentaenoic Acid Antagonize the Proinflammatory Interactions of Pneumolysin with Human Neutrophils

Pneumolysin (4.18 ng/ml)-mediated influx of Ca(2+) and augmentation of the chemoattractant-activated generation of reactive oxidants was antagonized by pretreatment of human neutrophils with the omega-3 polyunsaturated fatty acids docosahexaenoic acid and eicosapentaenoic acid (1.25 to 5 μg/ml). The...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cockeran, Riana, Theron, Annette J., Feldman, Charles, Mitchell, Timothy J., Anderson, Ronald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC427396/
https://ncbi.nlm.nih.gov/pubmed/15213185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4327-4329.2004
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