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An engineered genetic selection for ternary protein complexes inspired by a natural three-component hitchhiker mechanism

The bacterial twin-arginine translocation (Tat) pathway is well known to translocate correctly folded monomeric and dimeric proteins across the tightly sealed cytoplasmic membrane. We identified a naturally occurring heterotrimer, the Escherichia coli aldehyde oxidoreductase PaoABC, that is co-trans...

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Publicat a:Sci Rep
Autors principals: Lee, Hyeon-Cheol, Portnoff, Alyse D., Rocco, Mark A., DeLisa, Matthew P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273604/
https://ncbi.nlm.nih.gov/pubmed/25531212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07570
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