Arsenic trioxide in front-line therapy of acute promyelocytic leukemia (C9710): prognostic significance of FLT3 mutations and complex karyotype

The addition of arsenic trioxide (ATO) to frontline therapy of acute promyelocytic leukemia (APL) has been shown to result in significant improvements in disease-free survival (DFS). FLT3 mutations are frequently observed in APL, but its prognostic significance remains unclear. We analyzed 245 newly...

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Publicado en:Leuk Lymphoma
Autores principales: Poiré, Xavier, Moser, Barry K., Gallagher, Robert E., Laumann, Kristina, Bloomfield, Clara D., Powell, Bayard L., Koval, Gregory, Gulati, Kabir, Holowka, Nicholas, Larson, Richard A., Tallman, Martin S., Appelbaum, Frederick R., Sher, Dorie, Willman, Cheryl, Paietta, Elisabeth, Stock, Wendy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273565/
https://ncbi.nlm.nih.gov/pubmed/24160850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.842985
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