Arsenic trioxide in front-line therapy of acute promyelocytic leukemia (C9710): prognostic significance of FLT3 mutations and complex karyotype

The addition of arsenic trioxide (ATO) to frontline therapy of acute promyelocytic leukemia (APL) has been shown to result in significant improvements in disease-free survival (DFS). FLT3 mutations are frequently observed in APL, but its prognostic significance remains unclear. We analyzed 245 newly...

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Publié dans:Leuk Lymphoma
Auteurs principaux: Poiré, Xavier, Moser, Barry K., Gallagher, Robert E., Laumann, Kristina, Bloomfield, Clara D., Powell, Bayard L., Koval, Gregory, Gulati, Kabir, Holowka, Nicholas, Larson, Richard A., Tallman, Martin S., Appelbaum, Frederick R., Sher, Dorie, Willman, Cheryl, Paietta, Elisabeth, Stock, Wendy
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273565/
https://ncbi.nlm.nih.gov/pubmed/24160850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.842985
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