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Inherently chiral calix[4]arenes via oxazoline directed ortholithiation: synthesis and probe of chiral space

The diastereoselective oxazoline-directed lithiation of calix[4]arenes is reported with diastereoselective ratios of greater than 100:1 in some instances. Notably, it has been found that the opposite diastereomer can be accessed via this approach merely through the choice of an alkyllithium reagent....

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Библиографические подробности
Опубликовано в: :Beilstein J Org Chem
Главные авторы: Herbert, Simon A, van Laeren, Laura J, Castell, Dominic C, Arnott, Gareth E
Формат: Artigo
Язык:Inglês
Опубликовано: Beilstein-Institut 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273304/
https://ncbi.nlm.nih.gov/pubmed/25550740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.291
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