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4-1BB Ligand Signaling to T cells Limits T cell Activation
4-1BB ligand (4-1BBL) and its receptor, 4-1BB, are both induced on T cells after activation, however, little is known about the role of 4-1BBL. We now show that 4-1BBL can transmit signals that limit T cell effector activity under tolerogenic conditions. Cross-linking 4-1BBL inhibited IL-2 productio...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272921/ https://ncbi.nlm.nih.gov/pubmed/25404362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401383 |
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