Identification of antigen-specific B cell receptor sequences using public repertoire analysis

High-throughput sequencing allows detailed study of the B cell receptor (BCR) repertoire post-immunization but it remains unclear to what extent the de novo identification of antigen-specific sequences from the total BCR repertoire is possible. A Hib-MenC-TT conjugate vaccine containing H. influenza...

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Udgivet i:J Immunol
Main Authors: Trück, Johannes, Ramasamy, Maheshi N., Galson, Jacob D., Rance, Richard, Parkhill, Julian, Lunter, Gerton, Pollard, Andrew J., Kelly, Dominic F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272858/
https://ncbi.nlm.nih.gov/pubmed/25392534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401405
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