Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences

Generating a diverse B cell immunoglobulin repertoire is essential for protection against infection. The repertoire in humans can now be comprehensively measured by high-throughput sequencing. Using hepatitis B vaccination as a model, we determined how the total immunoglobulin sequence repertoire ch...

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Publicado en:EBioMedicine
Autores principales: Galson, Jacob D., Trück, Johannes, Fowler, Anna, Clutterbuck, Elizabeth A., Münz, Márton, Cerundolo, Vincenzo, Reinhard, Claudia, van der Most, Robbert, Pollard, Andrew J., Lunter, Gerton, Kelly, Dominic F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703725/
https://ncbi.nlm.nih.gov/pubmed/26844287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.11.034
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