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Inferring B cell specificity for vaccines using a Bayesian mixture model

BACKGROUND: Vaccines have greatly reduced the burden of infectious disease, ranking in their impact on global health second only after clean water. Most vaccines confer protection by the production of antibodies with binding affinity for the antigen, which is the main effector function of B cells. T...

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Pubblicato in:BMC Genomics
Autori principali: Fowler, Anna, Galson, Jacob D., Trück, Johannes, Kelly, Dominic F., Lunter, Gerton
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036227/
https://ncbi.nlm.nih.gov/pubmed/32087698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6571-7
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