Inferring B cell specificity for vaccines using a Bayesian mixture model

BACKGROUND: Vaccines have greatly reduced the burden of infectious disease, ranking in their impact on global health second only after clean water. Most vaccines confer protection by the production of antibodies with binding affinity for the antigen, which is the main effector function of B cells. T...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Fowler, Anna, Galson, Jacob D., Trück, Johannes, Kelly, Dominic F., Lunter, Gerton
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036227/
https://ncbi.nlm.nih.gov/pubmed/32087698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6571-7
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