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KRAS mutations in tumor tissue and plasma by different assays predict survival of patients with metastatic colorectal cancer

BACKGROUND: The optimal laboratory assay for detecting KRAS mutations in different biospecimens from patients with metastatic colorectal cancer (mCRC), and the clinical relevance of these gene alterations is still in question. We analyzed the prognostic–predictive relevance of KRAS status, determine...

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Bibliografische gegevens
Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Xu, Jian-Ming, Liu, Xiao-Jing, Ge, Fei-Jiao, Lin, Li, Wang, Yan, Sharma, Manish R, Liu, Ze-Yuan, Tommasi, Stefania, Paradiso, Angelo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272803/
https://ncbi.nlm.nih.gov/pubmed/25491325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0104-7
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