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KRAS mutation testing in metastatic colorectal cancer
The KRAS oncogene is mutated in approximately 35%-45% of colorectal cancers, and KRAS mutational status testing has been highlighted in recent years. The most frequent mutations in this gene, point substitutions in codons 12 and 13, were validated as negative predictors of response to anti-epidermal...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Baishideng Publishing Group Co., Limited
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468848/ https://ncbi.nlm.nih.gov/pubmed/23066310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i37.5171 |
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