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KRAS mutation testing in metastatic colorectal cancer

The KRAS oncogene is mutated in approximately 35%-45% of colorectal cancers, and KRAS mutational status testing has been highlighted in recent years. The most frequent mutations in this gene, point substitutions in codons 12 and 13, were validated as negative predictors of response to anti-epidermal...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tan, Cong, Du, Xiang
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Co., Limited 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468848/
https://ncbi.nlm.nih.gov/pubmed/23066310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i37.5171
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