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BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide and 30% of patients with CRC experience metastasis. Patients with metastatic colorectal cancer (mCRC) have a 5-year overall survival rate of <10%. V-raf murine sarcoma viral oncogene homolog B1 (BRAF) and V-Ki-ras2 Ki...

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Detalhes bibliográficos
Publicado no:Gastroenterol Rep (Oxf)
Main Authors: Li, Zi-Nan, Zhao, Lin, Yu, Li-Feng, Wei, Min-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333923/
https://ncbi.nlm.nih.gov/pubmed/32665851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gastro/goaa022
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