KRAS mutations in tumor tissue and plasma by different assays predict survival of patients with metastatic colorectal cancer

BACKGROUND: The optimal laboratory assay for detecting KRAS mutations in different biospecimens from patients with metastatic colorectal cancer (mCRC), and the clinical relevance of these gene alterations is still in question. We analyzed the prognostic–predictive relevance of KRAS status, determine...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Xu, Jian-Ming, Liu, Xiao-Jing, Ge, Fei-Jiao, Lin, Li, Wang, Yan, Sharma, Manish R, Liu, Ze-Yuan, Tommasi, Stefania, Paradiso, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272803/
https://ncbi.nlm.nih.gov/pubmed/25491325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-014-0104-7
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