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DNase Footprint Signatures are Dictated by Factor Dynamics and DNA Sequence

Genomic footprinting has emerged as an unbiased discovery method for transcription factor (TF) occupancy at cognate DNA in vivo. A basic premise of footprinting is that sequence-specific TF-DNA interactions are associated with localized resistance to nucleases, leaving observable signatures of cleav...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Sung, Myong-Hee, Guertin, Michael J., Baek, Songjoon, Hager, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272573/
https://ncbi.nlm.nih.gov/pubmed/25242143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.08.016
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